Hexarelin Dosing Guidelines

Effective Date: January 2025

Important Notice: This guide is for informational purposes only. Always talk to your doctor before starting or changing any medication.

1. What is Hexarelin?

Hexarelin (also known as Examorelin) is a synthetic growth hormone-releasing peptide (GHRP) composed of six amino acids. It's one of the most potent stimulators of growth hormone (GH) release, working by binding to ghrelin receptors in the brain and stimulating the pituitary gland to produce natural growth hormone. Unlike synthetic HGH, Hexarelin encourages your body to produce its own growth hormone, making it a more physiological approach to enhancing growth, recovery, and regeneration.

2. When is Hexarelin Used?

  • Muscle Growth & Athletic Performance:
    • Increases natural GH and IGF-1 production
    • Enhances muscle protein synthesis
    • Improves strength and recovery between workouts
    • Supports lean muscle development
  • Fat Loss & Body Composition:
    • Stimulates lipolysis (fat breakdown)
    • Helps reduce stubborn body fat
    • Improves overall body composition
    • Preserves lean mass during cutting phases
  • Recovery & Healing:
    • Accelerates recovery from training
    • Supports healing of tendons and joints
    • Reduces inflammation
    • Improves tissue repair and regeneration
  • Anti-Aging & Wellness:
    • Improves skin elasticity and collagen production
    • Enhances bone mineral density
    • Supports cardiovascular health
    • Improves sleep quality and energy levels
  • Cardiovascular Protection:
    • Provides cardioprotective effects
    • May improve heart function
    • Protects against ischemic damage

3. How to Take Hexarelin

A. For General Growth Hormone Enhancement

Beginner Protocol:

  • 50-100 mcg subcutaneously 1-2 times daily
  • Start with once daily dosing before bed
  • Can add morning dose after 1-2 weeks if well tolerated

Standard Protocol:

  • 100 mcg subcutaneously 2-3 times daily
  • Morning, post-workout, and before bed
  • Total daily dose: 200-300 mcg
  • Most common and well-researched dosing

Advanced Protocol:

  • 150-200 mcg subcutaneously 2-3 times daily
  • Total daily dose: 300-600 mcg
  • Only for experienced users
  • Requires careful monitoring

How to Take It:

  • Inject subcutaneously in abdomen or thigh
  • Rotate injection sites to prevent irritation
  • Take on empty stomach (60 minutes before/after food)
  • Best timing: morning, post-workout, bedtime

B. For Athletic Performance & Muscle Growth

Performance Enhancement Protocol:

  • Week 1-2: 100 mcg twice daily
  • Week 3-8: 100 mcg three times daily
  • Week 9-12: 150 mcg twice daily
  • Week 13-16: Off cycle (break period)

Muscle Building Protocol:

  • 200-300 mcg daily, split into 2-3 doses
  • Take 30-45 minutes before workouts
  • Continue for 12-16 weeks
  • Follow with 4-6 week break

C. For Fat Loss & Body Recomposition

Fat Loss Protocol:

  • 100 mcg morning (fasted state)
  • 100 mcg pre-cardio or pre-workout
  • 100 mcg before bed
  • Total: 300 mcg daily for 8-12 weeks

Body Recomposition Protocol:

  • Morning: 100 mcg (fasted)
  • Post-workout: 100 mcg
  • Before bed: 100 mcg
  • Combine with resistance training and proper nutrition
  • Cycle: 12 weeks on, 4 weeks off

D. For Recovery & Healing

Injury Recovery Protocol:

  • 100-150 mcg twice daily
  • Morning and evening administration
  • Continue for duration of healing (typically 4-8 weeks)
  • Can be combined with other healing peptides

Post-Surgery/Trauma Recovery:

  • 100 mcg three times daily
  • Space doses 6-8 hours apart
  • Duration: As recommended by physician
  • Monitor healing progress

E. For Anti-Aging & Wellness

Anti-Aging Protocol:

  • 50-100 mcg once or twice daily
  • Lower doses for long-term use
  • Preferably before bed for sleep benefits
  • Can be used for extended periods with breaks

Sleep & Recovery Protocol:

  • 100-200 mcg 30-60 minutes before bed
  • Single nightly dose
  • Improves deep sleep and GH pulse during sleep
  • 5 days on, 2 days off schedule

4. Special Considerations

  • Cycling Requirements:
    • Maximum continuous use: 12-16 weeks
    • Minimum break between cycles: 4 weeks
    • Prevents receptor desensitization
    • Maintains long-term effectiveness
  • Timing Considerations:
    • Best absorbed on empty stomach
    • Wait 30-60 minutes before eating
    • Avoid high-carb meals near injection time
    • Morning doses enhance daytime energy
  • Stacking Options:
    • Can combine with CJC-1295 for synergistic effect
    • Pairs well with Ipamorelin for reduced side effects
    • May stack with healing peptides (BPC-157, TB-500)
    • Avoid stacking multiple GHRPs
  • Individual Response:
    • Start with lower doses to assess tolerance
    • Some individuals more sensitive to effects
    • Adjust based on response and side effects
    • Monitor sleep quality and energy levels

5. Who Should Not Take Hexarelin & Safety Tips

  • Do Not Take If:
    • You have active cancer or history of cancer
    • You are pregnant or breastfeeding
    • You have severe heart disease
    • You have uncontrolled diabetes
    • You are under 18 years old (unless prescribed by doctor)
    • You have active pituitary tumors
  • Use Carefully If:
    • You have diabetes or insulin resistance
    • You have high blood pressure
    • You have history of heart problems
    • You have kidney or liver disease
    • You are taking other hormonal medications
    • You have sleep apnea

6. Possible Side Effects

Common Side Effects:

  • Increased appetite (less than GHRP-6)
  • Water retention or mild bloating
  • Tingling or numbness in extremities
  • Fatigue initially (improves with time)
  • Injection site reactions
  • Mild joint discomfort

Less Common Side Effects:

  • Elevated cortisol levels (dose-dependent)
  • Increased prolactin (at higher doses)
  • Headaches
  • Dizziness
  • Flushing of skin
  • Changes in blood sugar

Rare but Serious Side Effects:

  • Severe water retention
  • Significant hormonal imbalances
  • Cardiovascular effects at very high doses
  • Allergic reactions
  • Extreme fatigue or lethargy

7. What to Monitor

  • Hormone Levels:
    • IGF-1 levels: Check at baseline and every 4 weeks
    • Cortisol: Monitor if experiencing anxiety or sleep issues
    • Prolactin: Check if experiencing side effects
    • Blood glucose: Especially important for diabetics
  • Physical Markers:
    • Body composition changes
    • Strength and performance metrics
    • Recovery time between workouts
    • Sleep quality and duration
    • Energy levels throughout the day
  • Health Indicators:
    • Blood pressure
    • Heart rate
    • Water retention/edema
    • Joint comfort and mobility
    • Overall well-being

8. Storing Hexarelin

  • Lyophilized (Powder) Form:
    • Store in refrigerator (2-8°C/36-46°F)
    • Can be stored at room temperature briefly during shipping
    • Keep away from light and moisture
    • Check expiration date
  • After Reconstitution:
    • Must be refrigerated immediately
    • Use within 30 days of mixing
    • Store in original vial
    • Do not freeze
    • Keep away from direct light
    • Use bacteriostatic water for reconstitution

9. Patient Education

Helping you understand how to use Hexarelin properly is key to your success. Here's what you need to know:

A. How to Inject Hexarelin Correctly

  • Reconstitution Process:
    1. Clean vial tops with alcohol swab
    2. Add bacteriostatic water slowly down the side of vial
    3. Gently swirl (don't shake) until dissolved
    4. Solution should be clear without particles
    5. Calculate dose based on concentration
  • Steps to Inject Subcutaneously:
    1. Wash hands thoroughly
    2. Clean injection site with alcohol wipe
    3. Draw prescribed dose into insulin syringe
    4. Pinch skin at injection site
    5. Insert needle at 45-90 degree angle
    6. Inject slowly and steadily
    7. Remove needle and apply gentle pressure
    8. Dispose in sharps container
  • Injection Site Management:
    • Rotate between left and right abdomen
    • Alternative sites: outer thighs, upper arms
    • Avoid areas with scars, bruises, or irritation
    • Keep injection log to track sites

B. Why It's Important to Stick to Your Schedule

  • Maintaining GH Pulses:
    • Hexarelin has a short half-life (55 minutes)
    • Multiple daily doses maintain stable effects
    • Consistent timing optimizes natural GH rhythm
  • Preventing Desensitization:
    • Regular cycling prevents receptor downregulation
    • Breaks allow receptors to resensitize
    • Maintains long-term effectiveness
  • If You Miss a Dose:
    • Take as soon as remembered if within 2-3 hours
    • Skip if close to next scheduled dose
    • Don't double up doses
    • Maintain regular schedule going forward

C. Understanding Side Effects and When to Get Help

  • Managing Common Side Effects:
    • Water retention: Reduce sodium, stay hydrated
    • Appetite changes: Plan meals accordingly
    • Tingling: Usually temporary, reduces with time
    • Fatigue: May improve after first week
  • When to Contact Your Doctor:
    • Severe water retention or swelling
    • Persistent headaches or vision changes
    • Extreme fatigue or weakness
    • Signs of high cortisol (anxiety, insomnia)
    • Any concerning symptoms
  • Signs to Stop Immediately:
    • Severe allergic reaction
    • Chest pain or heart palpitations
    • Extreme swelling
    • Severe joint pain
    • Signs of infection at injection sites

D. Making Lifestyle Changes to Boost Results

  • Nutrition Optimization:
    • High protein diet (1g per pound body weight)
    • Time carbohydrates around workouts
    • Healthy fats for hormone production
    • Stay well-hydrated
    • Consider intermittent fasting
  • Training Protocol:
    • Resistance training 3-5 times per week
    • Focus on progressive overload
    • Include adequate recovery time
    • Add cardio for cardiovascular benefits
    • Prioritize compound movements
  • Sleep & Recovery:
    • Aim for 7-9 hours quality sleep
    • Maintain consistent sleep schedule
    • Create dark, cool sleeping environment
    • Manage stress through relaxation techniques
    • Consider meditation or yoga
  • Supplement Support:
    • Vitamin D3: 2000-5000 IU daily
    • Omega-3 fatty acids
    • Magnesium: 200-400mg before bed
    • Zinc: 15-30mg daily
    • Consider adaptogenic herbs for stress

E. Keep Up with Doctor Visits

  • Initial Assessment:
    • Baseline hormone panels
    • Body composition analysis
    • Cardiovascular assessment
    • Review of medical history
  • Regular Monitoring:
    • Monthly check-ins during first cycle
    • IGF-1 levels every 4-6 weeks
    • Body composition tracking
    • Side effect assessment
    • Dose adjustments as needed
  • Long-term Follow-up:
    • Comprehensive panels every 3 months
    • Annual cardiovascular evaluation
    • Ongoing assessment of benefits vs. risks
    • Planning of cycling schedules

Disclaimer: Always talk to your healthcare provider for advice tailored to your situation.